The EB House Austria is an EU Reference Center of Excellence for the rare genetic skin disease Epidermolysis bullosa (EB), affiliated with the University Hospital Salzburg and the Paracelsus Medical University. We consist of four units – an outpatient unit, academy, research unit, and clinical study center – and adopt a holistic approach to developing and delivering outstanding multi-disciplinary care to patients with EB.

We are looking for a full-time scientific associate to support various research projects aimed at investigating various pathobiological aspects and therapy of EB. EB is a devastating disease characterised by skin fragility due to mutations in genes encoding structural proteins necessary for maintaining proper adherence of the different skin layers to each other. As a result, the skin is prone to blistering and wounding after minimal trauma or friction. In the most severe subtypes, patients are prone to the development of life-threatening cutaneous squamous cell carcinoma.

 Full-time (40 hours/week) TA position for 1 year, with the potential to extend contract.
Start date as soon as possible. Minimum salary: 3.200 brutto/ month

Projects
+ Development of immune-therapeutic approaches against EB-associated cancer
+ Development of model systems for severe EB.

Candidate
The ideal candidate should be highly motivated, reliable, flexible, able to work both independently and as part of a team, and have strong time-management and communication skills. They should be interested in the scientific background of the group’s projects, have the ability to learn new techniques/assays, and be able to work precisely and document experiments properly.

Professional qualifications
+ MSc or BSc (or equivalent) in molecular or cell biology, genetics, biotechnology or similar
+ Technical/laboratory experience in:
               o PCR, cloning, immunofluorescence, immunohistochemistry, western blotting, flow
                  cytometry,  microscopy
               o cell culture (cultivation of different cell types)
+ Animal handling and experimentation (optimal: FELASA certificate or equivalent)
+ Fluent in written and spoken scientific English
+ Data analysis

Application
Please send your application (CV, motivation letter, and contact info of 3 references) to: Dr. Elisabeth Mayr, el.mayr@salk.at

Deadline: 30/04/2024